Synthesis, X-ray Analysis, and Biological Activities of Novel Oxazolidinethiones

Oxazolidinethione compounds were synthesized starting from racemic and enantiopure β‐amino alcohols. The molecular structure of oxazolidinethione 6a was elucidated by single‐crystal x‐ray crystallography. Oxazolidinethione compounds screened for antimicrobial activity showed mild minimum inhibitory...

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 51; no. 5; pp. 1264 - 1269
Main Authors Saygili, Nezire, Ozalp, Meral, Yildirim, Leyla Tatar
Format Journal Article
LanguageEnglish
Published HOBOKEN Blackwell Publishing Ltd 01.09.2014
Wiley
Wiley Subscription Services, Inc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
ANTIFERTILITY ACTIVITY
ASYMMETRIC ALDOL ADDITIONS
OXAZOLIDINONES
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Summary:Oxazolidinethione compounds were synthesized starting from racemic and enantiopure β‐amino alcohols. The molecular structure of oxazolidinethione 6a was elucidated by single‐crystal x‐ray crystallography. Oxazolidinethione compounds screened for antimicrobial activity showed mild minimum inhibitory concentration values.
Bibliography:ark:/67375/WNG-SND3XN2X-D
istex:81AE74CF918641AEC01D1F8DAD02AF0AEC7B0FEC
ArticleID:JHET1863
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.1863