Callosal lesions and delirious behavior during febrile illness

• Published in: Brain & development (Tokyo. 1979) Vol. 31; no. 2; pp. 158 - 162
• Main Authors: Okumura, Akihisa, Hayakawa, Fumio, Kato, Toru, Suzuki, Motomasa, Tsuji, Takeshi, Fukumoto, Yukiko, Nakata, Tomohiko, Watanabe, Kazuyoshi, Morishima, Tsuneo
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2009
• Subjects: Adolescent; Brain Diseases - pathology; Brain Diseases - physiopathology; Callosal lesion; Child; Child, Preschool; Consciousness; Corpus Callosum - pathology; Corpus Callosum - physiopathology; Delirious behavior; Delirium - pathology; Delirium - physiopathology; Diffusion Magnetic Resonance Imaging; Diffusion-weighted images; Electroencephalography; Febrile illness; Female; Fever - physiopathology; Humans; Male; Neurology; Retrospective Studies; Diffusion-weighted images; Febrile illness; Callosal lesion; Delirious behavior
• ISSN: 0387-7604; 1872-7131
• DOI: 10.1016/j.braindev.2008.06.002

Abstract We retrospectively reviewed electroencephalography and magnetic resonance imaging findings for 21 children exhibiting delirious behavior during febrile illness. Among these, five patients had transient callosal lesions with or without white matter lesions on diffusion-weighted images. We compared the clinical characteristics, duration, and components of delirious behavior, the duration and severity of reduced consciousness, and EEG findings among patients with or without callosal lesions. No significant differences were detected in these items according to the presence or absence of callosal lesions. Adding insight into the pathogenesis of this condition, our study revealed that callosal lesions are not uncommon in patients exhibiting delirious behavior during febrile illness.