Wireless and battery-free technologies for neuroengineering

• Published in: Nature biomedical engineering Vol. 7; no. 4; pp. 405 - 423
• Main Authors: Won, Sang Min, Cai, Le, Gutruf, Philipp, Rogers, John A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.04.2023; Nature Publishing Group
• Subjects: 631/378; 631/61; 639/166; Animal models; Animals; Biomedical and Life Sciences; Biomedical engineering; Biomedical Engineering/Biotechnology; Biomedicine; Brain research; Closed loops; Computer engineering; Electric Power Supplies; Interfaces; Models, Animal; Nanoparticles; Nervous system; Neurological disorders; Neurosciences; Physiology; Prostheses and Implants; Review Article; Social factors; Social interactions; Technology; Transplants & implants
• ISSN: 2157-846X; 2157-846X
• DOI: 10.1038/s41551-021-00683-3

Tethered and battery-powered devices that interface with neural tissues can restrict natural motions and prevent social interactions in animal models, thereby limiting the utility of these devices in behavioural neuroscience research. In this Review Article, we discuss recent progress in the development of miniaturized and ultralightweight devices as neuroengineering platforms that are wireless, battery-free and fully implantable, with capabilities that match or exceed those of wired or battery-powered alternatives. Such classes of advanced neural interfaces with optical, electrical or fluidic functionality can also combine recording and stimulation modalities for closed-loop applications in basic studies or in the practical treatment of abnormal physiological processes. This Review Article discusses progress in the development of miniaturized and ultralightweight devices for neuroengineering that are wireless, battery-free and fully implantable.