Design, Implementation, and Validation of a Pulsatile Heart Phantom Pump

The developments in Computed Tomography (CT) and Magnetic Resonance allow visualization of blood flow in vivo using these techniques. However, validation tests are needed to determine a gold standard. For the validation tests, controllable systems that can generate pulsatile flow are needed. In this...

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Bibliographic Details
Published inJournal of digital imaging Vol. 33; no. 5; pp. 1301 - 1305
Main Authors Tuncay, Volkan, Zijlstra, Jan, Oudkerk, Matthijs, van Ooijen, Peter M. A
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.10.2020
Springer Nature B.V
Subjects
Blood flow
Cardiac output
Circulatory system
Computed tomography
Flow distribution
Heart rate
Imaging
In vivo methods and tests
Magnetic resonance
Medicine
Medicine & Public Health
Microcontrollers
Original Paper
Radiology
Stroke
Stroke volume
Unsteady flow
Computed Tomography imaging
Phantom design
Pulsatile flow
Cardiovascular circulation mimicking
Pulsatile pump
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Summary:The developments in Computed Tomography (CT) and Magnetic Resonance allow visualization of blood flow in vivo using these techniques. However, validation tests are needed to determine a gold standard. For the validation tests, controllable systems that can generate pulsatile flow are needed. In this study, we aimed to develop an affordable pulsatile pump and an artificial circulatory system to simulate the blood flow for validation purposes. Initially, the prerequisites for the phantom were pulsating flow output equal to that of the human cardiac pulse pattern; the flow pattern of the mimicked cardiac output should be equal to that of a human, a variable stroke volume (40–120 ml/beat), and a variable heart rate (60–170 bpm). The developed phantom setup was tested with CT scanner. A washout profile was created based on the image intensity of the selected slice. The test was successful for a heart rate of 70 bpm and a stroke volume of 68 ml, but the system failed to work at various heartbeats and stroke volumes. This was due to the problems with software of the microcontroller. As conclusion in this study, we present a proof of concept for a pulsatile heart phantom pump that can be used in validation tests.
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ISSN:0897-1889
1618-727X
DOI:10.1007/s10278-020-00375-5