Continuous coloured light altered human brain haemodynamics and oxygenation assessed by systemic physiology augmented functional near-infrared spectroscopy

• Published in: Scientific reports Vol. 7; no. 1; pp. 10027 - 11
• Main Authors: Metz, A. J., Klein, S. D., Scholkmann, F., Wolf, U.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 30.08.2017; Nature Publishing Group
• Subjects: 631/443; 631/443/1784; 631/443/319; 631/443/376; 692/308; Adult; Aged; Carbon dioxide; Cerebrovascular Circulation; Circulatory system; Conductance; Female; Galvanic Skin Response; Heart Rate; Hemodynamics; Hemoglobin; Hemoglobins - metabolism; Humanities and Social Sciences; Humans; I.R. radiation; Infrared spectroscopy; Light; Male; Middle Aged; multidisciplinary; Oxygen Consumption; Oxygenation; Physiology; Prefrontal Cortex - metabolism; Prefrontal Cortex - physiology; Prefrontal Cortex - radiation effects; Random Allocation; Science; Science (multidisciplinary); Spectroscopy, Near-Infrared; Spectrum analysis; Visual Perception
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-017-09970-z

Exposure to artificial coloured light is unavoidable in our modern life, but we are only just beginning to understand the impact of coloured light on human physiology. The aim of the present study was to determine effects of coloured light exposure on human systemic and brain physiology using systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS). We measured changes in haemoglobin concentrations and tissue oxygen saturation in the left and right prefrontal cortices (L-PFC, R-PFC) by fNIRS, and also recorded skin conductance (SC), partial pressure of end-tidal CO 2 (P ET CO 2 ), and heart-rate variability variables. 17 healthy adults (median age: 29 years, range: 25–65 years, 6 women) were exposed to blue, red, green, or yellow light for 10 minutes. Pre-light and post-light conditions were in darkness. In the L-PFC the yellow evoked a brain activation. SC and P ET CO 2 did not change during any of the coloured light exposures, but SC increased and P ET CO 2 decreased for all colours (except green) in the post-light period. Changes in L-PFC haemoglobin concentration were also observed during the post-light period but have to be interpreted with care, because heart rate and SC increased while P ET CO 2 decreased. The detected effects are potentially of high relevance for choosing room lighting and may possibly be applied therapeutically.