Exposure to flupyradifurone affect health of biocontrol parasitoid Binodoxys communis (Hymenoptera: Braconidae) via disrupting detoxification metabolism and lipid synthesis

• Published in: Ecotoxicology and environmental safety Vol. 255; p. 114785
• Main Authors: Gao, Xueke, Zhao, Likang, Zhu, Xiangzhen, Wang, Li, Zhang, Kaixin, Li, Dongyang, Ji, Jichao, Niu, Lin, Luo, Junyu, Cui, Jinjie
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 15.04.2023; Elsevier
• Subjects: Animals; Binodoxys communis; Flupyradifurone; Hymenoptera; Insecticides - toxicity; Lipids; Pyridines - toxicity; QRT-PCR; Sublethal concentration; Transcriptome; Flupyradifurone; Binodoxys communis; Sublethal concentration; QRT-PCR; Transcriptome
• ISSN: 0147-6513; 1090-2414
• DOI: 10.1016/j.ecoenv.2023.114785

Assessing the potential effects of insecticides on beneficial biological control agents is key to facilitating the success of integrated pest management (IPM) approaches. Flupyradifurone (FPF) is a novel neonicotinoid insecticide that is replacing traditional neonicotinoids over a large geographical range to control pests. Binodoxys communis, is the dominant parasitic natural enemy of aphids. To date, no reports have addressed sublethal effects of FPF on B. communis. In this study, the lethal and sublethal effects of FPF on B. communis were investigated by indirect exposure to larvae and direct exposure to adults. Results showed that the sublethal LC10 and LC25 of FPF had negative effects on the biological parameters of B. communis, including significantly reducing survival rate, adult longevity, parasitism rate, and emergence rate, and significantly prolonging the developmental stages from egg to cocoons. In addition, we observed a transgenerational effect of FPF on the next generation (F1). RNA-Seq transcriptomic analysis identified a total of 1429 differentially expressed genes (DEGs) that were significantly changed between FPF-treated and control groups. These DEGs are mainly enriched in metabolic pathways such as peroxisomes, glutamate metabolism, carbon metabolism, fatty acid metabolism, and amino acid metabolism. This report is the first comprehensive evaluation of how FPF effects B. communis, which adds to the methods of assessing pesticide exposure in parasitic natural enemies. We speculate that the significant changes in pathways, especially those related to lipid synthesis, may be the reason for weakened parasitoid biocontrol ability. The present study provides new evidence for the toxic effects and environmental residue risk of FPF. [Display omitted] •FPF (LC10 and LC25) had negative effects on the biological parameters of B. communis.•FPF indicated transgenerational effect on the next generation at sublethal does.•Transcriptomic analysis identified DEGs are mainly enriched in metabolic pathways.•Pathway of detoxification and lipid synthesis were significantly influenced by FPF.