Prognostic factors for long-term improvement from stroke-related aphasia with adequate linguistic rehabilitation

In the past decade, several studies have reported potential prognostic factors for aphasia after stroke. However, these reports covered no more than 1 year after stroke onset, even though patients often continue to improve over longer periods. The present study included 121 patients with aphasia who...

Full description

Saved in:
Bibliographic Details
Published inNeurological sciences Vol. 40; no. 10; pp. 2141 - 2146
Main Authors Nakagawa, Yoshitaka, Sano, Yoko, Funayama, Michitaka, Kato, Masahiro
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.10.2019
Springer Nature B.V
Subjects
Adult
Aged
Aphasia
Aphasia - etiology
Aphasia - rehabilitation
Cognitive ability
Cohort Studies
Female
Handedness
Hemispheric laterality
Humans
Language Therapy - methods
Linguistics
Male
Medicine
Medicine & Public Health
Middle Aged
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Original
Original Article
Prognosis
Psychiatry
Rehabilitation
Retrospective Studies
Stroke
Stroke Rehabilitation - methods
Superior temporal gyrus
Temporal gyrus
Aphasia recovery
Long-term prognosis
Phonology
Wernicke’s area
Semantics
Age
Online AccessGet full text

Cover

More Information
Summary:In the past decade, several studies have reported potential prognostic factors for aphasia after stroke. However, these reports covered no more than 1 year after stroke onset, even though patients often continue to improve over longer periods. The present study included 121 patients with aphasia who received cognitive-based linguistic rehabilitation for at least 2 years post-onset. All were right-handed and had a lesion only in the left hemisphere. Aphasia outcome was predicted using multiple linear regression analysis. Age at onset, lesion in the left superior temporal gyrus including Wernicke’s area, and baseline linguistic abilities including aphasia severity and both phonological and semantic functions were significant predictors of long-term aphasia outcome. These findings suggest that the long-term outcome of aphasia following adequate linguistic rehabilitation can be predicted by age at onset, lesion area, and baseline linguistic abilities and that linguistic rehabilitation is particularly recommended for younger individuals with aphasia.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-019-03956-7