glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells

Null mutations of glass specifically remove photoreceptor cells, leaving other cell types intact. We have isolated the glass gene and have shown that its transcript encodes a putative protein of 604 amino acids with five zinc-fingers. The glass product may be a transcription factor required for the...

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Bibliographic Details
Published inNature (London) Vol. 340; no. 6234; pp. 531 - 536
Main Authors Moses, K, Ellis, M.C, Rubin, G.M
Format Journal Article
LanguageEnglish
Published England 17.08.1989
Subjects
Animals
Base Sequence
cells
DNA - analysis
Drosophila
Drosophila - genetics
Gene Expression Regulation
genes
Molecular Sequence Data
Mutation
phenotype
Photoreceptor Cells - physiology
photoreceptors
proteins
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Summary:Null mutations of glass specifically remove photoreceptor cells, leaving other cell types intact. We have isolated the glass gene and have shown that its transcript encodes a putative protein of 604 amino acids with five zinc-fingers. The glass product may be a transcription factor required for the development of a single neuronal cell type.
ISSN:0028-0836
1476-4687
DOI:10.1038/340531a0