Methods of Treatment and Outcome for Ovarian Germ Cell Tumors

• Published in: Indian journal of surgical oncology Vol. 10; no. 4; pp. 640 - 642
• Main Authors: Elbrashy, Assem Ahmed, Kamal, Amr, Fahim, Mohamed Ibrahim
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.12.2019; Springer Nature B.V
• Subjects: Cancer surgery; Chemotherapy; Hysterectomy; Medicine; Medicine & Public Health; Oncology; Original; Original Article; Surgery; Surgical Oncology; Tumors; Germ cell ovarian tumors (GCOT); Cytoreductive surgery (CRS); Management
• ISSN: 0975-7651; 0976-6952
• DOI: 10.1007/s13193-019-00960-3

Ovarian germ cell tumors account for about 15–20% of all ovarian tumors. They occur mainly in girls, adolescents, and young adults. This study aims to assess the different clinico-pathological factors of ovarian germ cell tumors, treatment methods, and outcome. This is a retrospective observational cohort study including 54 cases with OGCTs which were studied from the period between January 2013 and December 2016. The study was performed at National Cancer Institute (NCI)–Cairo University, Egypt. All cases had cytoreductive surgery in the form of unilateral salpingo-oophorectomy in 42 cases and total abdominal hysterectomy in 12 cases. Complete cytoreduction was achieved in 46 cases while 8 cases had residual disease after surgery. Adjuvant chemotherapy was given in 26 cases (stage II, III, and IV malignant OGCTs). The main treatment of ovarian germ cell tumors is complete cytoreductive surgery which can be achieved in many cases with unilateral salpingo-oophorectomy. Adjuvant chemotherapy is highly recommended in case of malignant ovarian germ cell tumors.