Are engineered proteins getting competition from RNA?

Progress in several areas of research is pushing back the supposed limitations of nucleic acid structure and function. New ligand-binding and catalytic RNAs are being created at a rapid pace. Some engineered RNAs offer potential as therapeutic agents whereas others can be used as model systems to st...

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Bibliographic Details
Published inCurrent opinion in biotechnology Vol. 7; no. 4; pp. 442 - 448
Main Author Breaker, Ronald R
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.1996
Subjects
Base Sequence
Molecular Sequence Data
Nucleic Acid Conformation
Protein Engineering
Recombinant Proteins - chemistry
Recombinant Proteins - metabolism
RNA - chemistry
RNA - metabolism
RNA, Catalytic - chemistry
RNA, Catalytic - genetics
RNA, Catalytic - metabolism
RNA-Binding Proteins - chemistry
RNA-Binding Proteins - metabolism
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Summary:Progress in several areas of research is pushing back the supposed limitations of nucleic acid structure and function. New ligand-binding and catalytic RNAs are being created at a rapid pace. Some engineered RNAs offer potential as therapeutic agents whereas others can be used as model systems to study the principles that direct structure formation, molecular recognition and catalytic function by nucleic acids.
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SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:0958-1669
1879-0429
DOI:10.1016/S0958-1669(96)80122-4