Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice

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Bibliographic Details
Published inCellular & molecular immunology Vol. 18; no. 4; pp. 1070 - 1073
Main Authors Sun, Shihui, He, Lei, Zhao, Zhongpeng, Gu, Hongjing, Fang, Xin, Wang, Tiecheng, Yang, Xiaolan, Chen, Shaolong, Deng, Yongqiang, Li, Jiangfan, Zhao, Jian, Li, Liang, Li, Xinwang, He, Peng, Li, Ge, Li, Hao, Zhao, Yuee, Gao, Chunrun, Lang, Xiaoling, Wang, Xin, Fei, Guoqiang, Li, Yan, Geng, Shusheng, Gao, Yuwei, Wei, Wenjin, Hu, Zhongyu, Han, Gencheng, Sun, Yansong
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.04.2021
Nature Publishing Group
Subjects
631/250/255/2514
692/53/2423
Angiotensin-Converting Enzyme 2 - chemistry
Animals
Antibodies
Antibodies, Neutralizing - immunology
Antibodies, Viral - immunology
Biomedical and Life Sciences
Biomedicine
CHO Cells
Correspondence
COVID-19 - immunology
COVID-19 - prevention & control
COVID-19 Vaccines - genetics
COVID-19 Vaccines - immunology
Cricetulus
Immunoglobulin Fc Fragments - genetics
Immunology
Macaca fascicularis
Medical Microbiology
Mice
Mice, Inbred BALB C
Microbiology
Molecular Docking Simulation
Protein Domains - immunology
SARS-CoV-2 - immunology
Severe acute respiratory syndrome coronavirus 2
Spike Glycoprotein, Coronavirus - chemistry
Spike Glycoprotein, Coronavirus - immunology
Vaccine
Vaccines, Synthetic - genetics
Vaccines, Synthetic - immunology
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ISSN:1672-7681
2042-0226
2042-0226
DOI:10.1038/s41423-021-00658-z