Physiologic underpinnings for clinical problems in moderately preterm and late preterm infants

This article highlights some of the important developmental characteristics that underpin common problems seen in moderate and late preterm infants. Preterm birth is associated with an increased prevalence of clinical problems caused by functional immaturities in a wide variety of organ systems, acq...

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Bibliographic Details
Published inClinics in perinatology Vol. 40; no. 4; p. 645
Main Authors Sahni, Rakesh, Polin, Richard A
Format Journal Article
LanguageEnglish
Published United States 01.12.2013
Subjects
Gestational Age
Humans
Infant, Newborn
Infant, Premature - immunology
Infant, Premature - physiology
Infant, Premature, Diseases - immunology
Infant, Premature, Diseases - physiopathology
Prevalence
Immunologic immaturity
Glucose homeostasis
Gastrointestinal immaturity
Thermoregulation
Hepatic immaturity
Brain dysmaturity
Respiratory morbidities
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Summary:This article highlights some of the important developmental characteristics that underpin common problems seen in moderate and late preterm infants. Preterm birth is associated with an increased prevalence of clinical problems caused by functional immaturities in a wide variety of organ systems, acquired problems, and problems associated with inadequate monitoring and/or follow-up plans. There are variations in the degree of maturation among infants of similar gestational ages because the developmental process is nonlinear. Therefore, different organ systems mature at rates and trajectories that are specific to their functions. A better understanding of these principles can help guide optimal treatment strategies.
ISSN:1557-9840
DOI:10.1016/j.clp.2013.07.012