Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order

Halobacteria, a class of Euryarchaeota are extremely halophilic archaea that can adapt to a wide range of salt concentration generally from 10% NaCl to saturated salt concentration of 32% NaCl. It consists of the orders: Halobacteriales, Haloferaciales and Natriabales. Pan-genome analysis of class H...

Full description

Saved in:
Bibliographic Details
Published inScientific reports Vol. 10; no. 1; p. 21205
Main Authors Gaba, Sonam, Kumari, Abha, Medema, Marnix, Kaushik, Rajeev
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 03.12.2020
Nature Publishing Group
Subjects
631/114/2164
631/114/2400
631/114/739
631/326/26/2526
Datasets as Topic
Environmental information
Euryarchaeota - classification
Euryarchaeota - genetics
Evolutionary genetics
Gene transfer
Genes
Genetic transformation
Genome, Archaeal
Genomes
Halobacteria
Halophilic archaea
Horizontal transfer
Humanities and Social Sciences
Information processing
multidisciplinary
Phylogeny
Probability
RNA, Ribosomal, 16S - genetics
Science
Science (multidisciplinary)
Sodium chloride
Transcription
Online AccessGet full text

Cover

More Information
Summary:Halobacteria, a class of Euryarchaeota are extremely halophilic archaea that can adapt to a wide range of salt concentration generally from 10% NaCl to saturated salt concentration of 32% NaCl. It consists of the orders: Halobacteriales, Haloferaciales and Natriabales. Pan-genome analysis of class Halobacteria was done to explore the core (300) and variable components (Softcore: 998, Cloud:36531, Shell:11784). The core component revealed genes of replication, transcription, translation and repair, whereas the variable component had a major portion of environmental information processing. The pan-gene matrix was mapped onto the core-gene tree to find the ancestral (44.8%) and derived genes (55.1%) of the Last Common Ancestor of Halobacteria. A High percentage of derived genes along with presence of transformation and conjugation genes indicate the occurrence of horizontal gene transfer during the evolution of Halobacteria. A Core and pan-gene tree were also constructed to infer a phylogeny which implicated on the new super-order comprising of Natrialbales and Halobacteriales.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-77723-6