Anatomy of teleost fish immune structures and organs

• Published in: Immunogenetics (New York) Vol. 73; no. 1; pp. 53 - 63
• Main Authors: Bjørgen, Håvard, Koppang, Erling Olaf
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2021; Springer Nature B.V
• Subjects: Allergology; Anatomy; Biomedical and Life Sciences; Biomedicine; Cell Biology; Fish; Fish Immunology; Gene Function; Human Genetics; Immunology; Lymphoid tissue; Morphology; Organs; Pharynx; Physical characteristics; Review; Salmo salar; Salmon; Salmonids; Spleen; ILT; Spleen; Immune organ; Bursa; Morphology; Fish; Histology; Lymphoid tissue; Kidney; Thymus
• ISSN: 0093-7711; 1432-1211; 1432-1211
• DOI: 10.1007/s00251-020-01196-0

The function of a tissue is determined by its construction and cellular composition. The action of different genes can thus only be understood properly when seen in the context of the environment in which they are expressed and function. We now experience a renaissance in morphological research in fish, not only because, surprisingly enough, large structures have remained un-described until recently, but also because improved methods for studying morphological characteristics in combination with expression analysis are at hand. In this review, we address anatomical features of teleost immune tissues. There are approximately 30,000 known teleost fish species and only a minor portion of them have been studied. We aim our review at the Atlantic salmon ( Salmo salar ) and other salmonids, but when applicable, we also present information from other species. Our focus is the anatomy of the kidney, thymus, spleen, the interbranchial lymphoid tissue (ILT), the newly discovered salmonid cloacal bursa and the naso-pharynx associated lymphoid tissue (NALT).