How a single receptor-like kinase exerts diverse roles: lessons from FERONIA

FERONIA (FER) is a member of the Catharanthus roseus receptor-like kinase 1-like (CrRLK1L) protein subfamily, which participates in reproduction, abiotic stress, biotic stress, cell growth, hormone response, and other molecular mechanisms of plants. However, the mechanism by which a single RLK is ca...

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Published inMolecular horticulture Vol. 2; no. 1; pp. 25 - 11
Main Authors Wang, Gaopeng, Zhao, Zhifang, Zheng, Xinhang, Shan, Wenfeng, Fan, Jiangbo
Format Journal Article
LanguageEnglish
Published London Springer Nature B.V 18.11.2022
BioMed Central
BMC
Subjects
Abiotic stress
Cell growth
Communication
FERONIA
Immunity
Kinases
Ligands
Peptides
Perceptions
Plant reproduction
Proteins
Regulation mechanism
Review
Roles
Signal transduction
Signaling pathway
Sperm
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Summary:FERONIA (FER) is a member of the Catharanthus roseus receptor-like kinase 1-like (CrRLK1L) protein subfamily, which participates in reproduction, abiotic stress, biotic stress, cell growth, hormone response, and other molecular mechanisms of plants. However, the mechanism by which a single RLK is capable of mediating multiple signals and activating multiple cellular responses remains unclear. Here, we summarize research progress revealing the spatial–temporal expression of FER, along with its co-receptors and ligands determined the function of FER signaling pathway in multiple organs. The specificity of the FER signaling pathway is proposed to operate under a four-layered mechanism: (1) Spatial–temporal expression of FER, co-receptors, and ligands specify diverse functions, (2) Specific ligands or ligand combinations trigger variable FER signaling pathways, (3) Diverse co-receptors confer diverse FER perception and response modes, and (4) Unique downstream components that modify FER signaling and responses. Moreover, the regulation mechanism of the signaling pathway- appears to depend on the interaction among the ligands, RLK receptors, co-receptors, and downstream components, which may be a general mechanism of RLKs to maintain signal specificity. This review will provide a insight into understanding the specificity determination of RLKs signaling in both model and horticultural crops.
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ISSN:2730-9401
2730-9401
DOI:10.1186/s43897-022-00046-9