Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy

• Published in: Journal of postgraduate medicine Vol. 60; no. 4; pp. 394 - 396
• Main Authors: Payabvash, S, McKinney, A M, Nascene, D, Cayci, Z
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.10.2014; Medknow Publications & Media Pvt. Ltd
• Subjects: Adult; Care and treatment; Case studies; Complications and side effects; Cytotoxicity; Diagnosis; Dosage and administration; Encephalopathy; Female; Hemorrhage; Humans; Liver; Liver Transplantation; Magnetic Resonance Imaging; Patients; Posterior Leukoencephalopathy Syndrome - chemically induced; Posterior Leukoencephalopathy Syndrome - diagnosis; Postoperative Complications - chemically induced; Postoperative Complications - diagnosis; Risk factors; Siderosis - complications; Siderosis - pathology; Subarachnoid hemorrhage; Subarachnoid Hemorrhage - chemically induced; Subarachnoid Hemorrhage - diagnosis; Tacrolimus; Tacrolimus - adverse effects; Transplants & implants
• ISSN: 0022-3859; 0972-2823
• DOI: 10.4103/0022-3859.143968

In this paper, we present a patient of posterior reversible encephalopathy syndrome (PRES), following liver transplantation, that showed evidence of chronic subarachnoid hemorrhage (SAH) on 2-month follow-up susceptibility-weighted-images (SWI) scan with cerebellar superficial siderosis. Of note, PRES patients with transplantation (specially bone marrow transplant) and those who are therapeutically anticoagulated are more likely to have hemorrhage, [6] and may benefit the most from evaluation with SWI.