Cathepsin G increases MMP expression in normal human fibroblasts through fibronectin fragmentation, and induces the conversion of proMMP-1 to active MMP-1

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Bibliographic Details
Published inJournal of dermatological science Vol. 53; no. 2; pp. 150 - 152
Main Authors Son, Eui Dong, Kim, Hyaekyoung, Choi, Hyunjung, Lee, So Hee, Lee, Jin Young, Kim, Sujung, Closs, B, Lee, Sera, Chung, Jin Ho, Hwang, Jae Sung
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.02.2009
Subjects
Adult
Age Factors
Aged
Aging
Buttocks
Cathepsin G
Cathepsins - antagonists & inhibitors
Cathepsins - metabolism
Cells, Cultured
Dermatology
Enzyme Activation
Enzyme Precursors - metabolism
Extracellular matrix
Female
Fibroblasts - drug effects
Fibroblasts - enzymology
Fibroblasts - radiation effects
Fibronectin
Fibronectin fragments
Fibronectins - metabolism
Humans
Male
Matrix Metalloproteinase 1 - genetics
Matrix Metalloproteinase 1 - metabolism
Matrix Metalloproteinase 2 - metabolism
Middle Aged
Peptide Fragments - metabolism
RNA, Messenger - metabolism
Serine Endopeptidases - metabolism
Serine Proteinase Inhibitors - pharmacology
Skin - cytology
Skin - drug effects
Skin - enzymology
Skin - radiation effects
Skin aging
Ultraviolet Rays
Extracellular matrix
Fibronectin fragments
Skin aging
Fibronectin
Cathepsin G
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Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0923-1811
1873-569X
DOI:10.1016/j.jdermsci.2008.08.006