Aminolevulinic acid (ALA): photodynamic detection and potential therapeutic applications

Abstract Aminolevulinic acid (ALA) is a heme precursor that may have potential applications for photodynamic detection and photodynamic therapy–based treatment of solid tumors in a variety of malignancies. ALA may have a role in other applications in surgical oncology based on its ability to discrim...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of surgical research Vol. 181; no. 2; pp. 262 - 271
Main Authors Nokes, Brandon, MS, Apel, Matt, MD, Jones, Carol, MD, Brown, Gabrielle, MS, Lang, Julie E., MD, FACS
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.2013
Subjects
ALA
Aminolevulinic acid
Aminolevulinic Acid - therapeutic use
Antineoplastic Agents - therapeutic use
Cancer
Drug Administration Routes
Drug Approval
Fluorescence
Humans
Neoplasms - diagnosis
Neoplasms - drug therapy
Photochemotherapy
Photodynamic
Photosensitizing Agents - therapeutic use
Surgery
Fluorescence
Photodynamic
Aminolevulinic acid
ALA
Cancer
Online AccessGet full text

Cover

More Information
Summary:Abstract Aminolevulinic acid (ALA) is a heme precursor that may have potential applications for photodynamic detection and photodynamic therapy–based treatment of solid tumors in a variety of malignancies. ALA may have a role in other applications in surgical oncology based on its ability to discriminate neoplastic tissue from adjacent normal tissue. In this review, we provide a comprehensive summary of the published studies of ALA in noncutaneous solid malignancies.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2013.02.002