Visualization of electrical activity in the cervical spinal cord and nerve roots after ulnar nerve stimulation using magnetospinography

• Published in: Clinical neurophysiology Vol. 131; no. 10; pp. 2460 - 2468
• Main Authors: Miyano, Yuki, Kawabata, Shigenori, Akaza, Miho, Sekihara, Kensuke, Hoshino, Yuko, Sasaki, Toru, Watanabe, Taishi, Kim, SukChan, Sato, Shinji, Mitani, Yuki, Adachi, Yoshiaki, Okawa, Atsushi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2020
• Subjects: Evoked magnetic field; Magnetoneurography; Magnetospinography; Somatosensory evoked potential; Ulnar nerve; MSG; UGRENS; Ulnar nerve; CSP; Magnetoneurography; Magnetospinography; Evoked magnetic field; SQUID; Somatosensory evoked potential; DSSP; SEP
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2020.07.009

•We successfully obtained magnetospinography (MSG) measurements in spinal cord after ulnar nerve stimulation.•Neural currents flow into the intervertebral foramina between C6/7 and T1/2.•MSG with ulnar nerve stimulation at elbow is effective for lower cervical spinal cord activation. To establish a method for magnetospinography (MSG) measurement after ulnar nerve stimulation and to clarify its characteristics. Using a 132-channel magnetoneurography system with a superconducting quantum interference device, cervical MSG measurements were obtained for 10 healthy volunteers after stimulation of the ulnar nerve at the elbow and the wrist, and neural current distribution was calculated and superimposed on the cervical X-ray images. Neuromagnetic signals were obtained in all participants after applying the stimulus artifact removal algorithm. The measured magnetic field intensity after elbow stimulation was about twice that after wrist stimulation. Calculated neural currents flowed into the intervertebral foramina at C6/7 to T1/2 and propagated cranially along the spinal canal. The conduction velocity from the peak latency of inward currents at C5-C7 was 73.4 ± 19.6 m/s. We successfully obtained MSG measurements after ulnar nerve stimulation. The neural currents flowed into the spinal canal from more caudal segments after ulnar nerve stimulation compared with median nerve stimulation, and these MSG measurements were effective in examining the spinal tracts at C5/6/7. This is the first report on the use of MSG to visualize electrical activity in the cervical spinal cord and nerve root after ulnar nerve stimulation.