Prescription analgesia and adjuvant use by pain severity at admission among nursing home residents with non-malignant pain

• Published in: European journal of clinical pharmacology Vol. 76; no. 7; pp. 1021 - 1028
• Main Authors: Lapane, Kate L., Hume, Anne L., Morrison, Reynolds A., Jesdale, Bill M.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2020; Springer Nature B.V
• Subjects: Adjuvants; Aged; Aged, 80 and over; Analgesia; Analgesics; Analgesics - therapeutic use; Anticonvulsants - therapeutic use; Antidepressive Agents - therapeutic use; Biomedical and Life Sciences; Biomedicine; Chemotherapy, Adjuvant; Cognitive ability; Female; gamma-Aminobutyric Acid - analogs & derivatives; gamma-Aminobutyric Acid - therapeutic use; Glucocorticoids - therapeutic use; Humans; Male; Middle Aged; Neuromuscular Agents - therapeutic use; Nursing homes; Nursing Homes - statistics & numerical data; Pain; Pain - drug therapy; Pain perception; Pharmacoepidemiology and Prescription; Pharmacology/Toxicology; Severity of Illness Index; Nursing homes; Pain; Analgesics; Pain severity
• ISSN: 0031-6970; 1432-1041; 1432-1041
• DOI: 10.1007/s00228-020-02878-0

Objective We estimated the use of prescribed analgesics and adjuvants among nursing home residents without cancer who reported pain at their admission assessment, in relation to resident-reported pain severity. Methods Medicare Part D claims were used to define 3 classes of analgesics and 7 classes of potential adjuvants on the 21st day after nursing home admission (or the day of discharge for residents discharged before that date) among 180,780 residents with complete information admitted between January 1, 2011 and December 9, 2016, with no cancer diagnosis. Results Of these residents, 27.9% reported mild pain, 46.6% moderate pain, and 25.6% reported severe pain. The prevalence of residents in pain without Part D claims for prescribed analgesic and/or adjuvant medications was 47.3% among those reporting mild pain, 35.7% among those with moderate pain, and 24.8% among those in severe pain. Among residents reporting severe pain, 33% of those ≥ 85 years of age and 35% of those moderately cognitively impaired received no prescription analgesics/adjuvants. Use of all classes of prescribed analgesics and adjuvants increased with resident-reported pain severity, and the concomitant use of medications from multiple classes was common. Conclusion Among nursing home residents with recognized pain, opportunities to improve the pharmacologic management of pain, especially among older residents, and those living with cognitive impairments exist.