Deterioration in quality of life following hip fracture : A prospective study

• Published in: Osteoporosis international Vol. 11; no. 5; pp. 460 - 466
• Main Authors: RANDELL, A. G, NGUYEN, T. V, BHALERAO, N, SILVERMAN, S. L, SAMBROOK, P. N, EISMAN, J. A
• Format: Journal Article
• Language: English
• Published: London Springer 01.05.2000; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Arthritis; Biological and medical sciences; Case-Control Studies; Disease; Diseases of the osteoarticular system; Female; Follow-Up Studies; Fractures; Health Status Indicators; Hip Fractures - etiology; Hip Fractures - rehabilitation; Hip joint; Hospitals; Humans; Longitudinal studies; Male; Medical research; Medical sciences; Morbidity; Osteoporosis; Osteoporosis - complications; Osteoporosis. Osteomalacia. Paget disease; Prospective Studies; Quality of Life; Questionnaires; Surveys and Questionnaires; Trauma; Validity; Sydney New South Wales Australia; Los Angeles California; California; Australia; United States > US; Human; Femoral neck; Diseases of the osteoarticular system; Lower limb; Bone disease; Fracture; Trauma; Epidemiology; Hip; Morbidity; Quality of life; Osteoporosis; Follow up study; Complication; Bone; Elderly; Public health
• ISSN: 0937-941X; 1433-2965
• DOI: 10.1007/s001980070115

To examine longitudinal change in health-related quality of life (HRQoL) following hip fracture in elderly subjects, 32 patients with hip fractures and 29 sex-matched non-fracture control subjects (mean +/- SD age 82 +/- 8 and 86 +/- 6 years respectively) were enrolled in a prospective, case-control study. Fracture subjects completed a generic questionnaire, Short Form 36 (SF-36), and a disease-targeted measure, the revised Osteoporosis Assessment Questionnaire (OPAQ2), on two separate occasions, within 1 week of fracture and 12-15 weeks after fracture. Controls completed both questionnaires on two occasions 12 weeks apart. SF-36 scores were significantly correlated with OPAQ2 in comparable domains of Physical Function (r = 0.76), General Health (r = 0.70) and Mental Health/Tension (r=0.86). Control subjects had stable scores with the OPAQ2 and SF-36. At 3 months after fracture there was a significant reduction in HRQoL in the SF-36 domains Physical Function (-51%), Vitality (-24%) and Social Function (-26%) and in the OPAQ2 domains Physical Function (-20%), Social Activity (-49%) and General Health (-24%). Hip fracture patients thus had a lower baseline HRQoL and experienced a significant deterioration in HRQoL after hip fracture on both the SF-36 and OPAQ2. HRQoL should be part of a comprehensive assessment of the costs of osteoporosis including fracture-associated morbidity.