Lip Reshaping with LOVE Approach: A Prospective Analysis Based on Two Hyaluronic Acid Fillers

• Published in: Plastic and reconstructive surgery. Global open Vol. 9; no. 11; p. e3957
• Main Authors: Bertossi, Dario, Nocini, Riccardo, van der Lei, Berend, Magistretti, Philippe, Gualdi, Alessandro, Pirayesh, Ali, Marchetti, Alberto
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 01.11.2021; Wolters Kluwer
• Subjects: Cosmetic; Original
• ISSN: 2169-7574; 2169-7574
• DOI: 10.1097/GOX.0000000000003957

Aesthetic improvement of the lips with hyaluronic acid fillers is a popular procedure. A comprehensive, modular, and highly individualizable method has been developed: the Lip Omnicomprehensive Volume Enhancement (LOVE) approach. The present study assessed the safety and effectiveness of LOVE across different patient age groups. This was a prospective, single-center study of women aged 20-70 years seeking nonsurgical lip enhancement or asymmetry correction. Three equally sized groups were formed based on patient age: 20-34, 35-45, and 46 years or older. Individualized treatment plans were developed taking into account patient preferences expressed in a pre-injection questionnaire. Treatment used one or more of the three modules of LOVE: lip shape [vermilion border, Vycross (VYC)-17.5]; volume (vermilion body, VYC-17.5); and hydration (submucosal area, VYC-12). Follow-up lasted 6 months. Sixty patients were enrolled (mean age: 41.3 ± 13.3 years; n = 20 per age group), all of whom were White. Most were treated with all three LOVE modules. Mean filler quantities increased with age: 20-34 years, 1.1 ± 0.1 mL; 35-45 years, 1.5 ± 0.1 mL; 46 years or older, 1.6 mL ± 0.2 mL. Mean patient satisfaction at 4 weeks [on a seven-point scale from 0 (extremely dissatisfied) to 6 (extremely satisfied)] was 4.8-4.9 in each age group. Apart from minor and transient edema/bruising, there was only one complication: a case of lumps that resolved with home massage. The LOVE approach is safe and effective across a range of ages, with high levels of patient satisfaction.