Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan

Bone banks are necessary for providing biological allografts for a series of orthopedic procedures. As nations cope with new realities driven by the 2019 coronavirus disease (COVID-19) pandemic, health-care providers, institutions, and patients share a particular concern about the effect of COVID-19...

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Published inCell and tissue banking Vol. 22; no. 4; pp. 703 - 709
Main Authors Uchida, Kentaro, Mukai, Manabu, Miyagi, Masayuki, Fukushima, Kensuke, Uchiyama, Katsufumi, Nakayama, Akiko, Matsumoto, Mai, Takahira, Naonobu, Urabe, Ken, Takaso, Masashi, Inoue, Gen
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 01.12.2021
Springer Nature B.V
Subjects
Allografts
Asymptomatic
Biomedical and Life Sciences
Biomedicine
Blood & organ donations
Bone grafts
Cell Biology
Coronaviruses
COVID-19
Cryopreservation
Disease transmission
Donors
Full Length Paper
Life Sciences
Pandemics
Patients
State of emergency
Transplant Surgery
Transplantation
COVID-19
Bone bank
Allograft bone
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Summary:Bone banks are necessary for providing biological allografts for a series of orthopedic procedures. As nations cope with new realities driven by the 2019 coronavirus disease (COVID-19) pandemic, health-care providers, institutions, and patients share a particular concern about the effect of COVID-19 on organ donation and transplantation. Here, we describe the management of the Kitasato University Bone Bank during the state of emergency declared in response to COVID-19. Living donors received pre-operative screening by PCR, and allograft bone from COVID-19-negative donors was cryopreserved as transplantable tissues. The weekly rate of infection gradually increased from February 2–9 to April 5–11 in the dead donor-derived allograft bone-harvesting region covered by the Bank. It is becoming clear that the virus can be transmitted by asymptomatic patients, and that this route may have facilitated the spread of COVID-19. Therefore, the Bank stopped dead donor donation to consider the safety of medical staff. Three recipients received bone allografts following pre-operative COVID-19 screening by PCR. All patients were asymptomatic after bone allograft. Our experience may provide helpful information for the management of tissue banks.
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ISSN:1389-9333
1573-6814
DOI:10.1007/s10561-021-09908-w