Characterizing the Right Ventricle: Advancing Our Knowledge

Our ability to evaluate the right ventricle (RV) in pulmonary hypertension has traditionally been quite limited: the RV's complex anatomy is not adequately represented by 2-dimensional imaging, and our understanding of what is an adaptive and maladaptive RV response is incomplete. However, meas...

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Bibliographic Details
Published inThe American journal of cardiology Vol. 110; no. 6; pp. S3 - S8
Main Authors Chin, Kelly M., Coghlan, Gerry
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 15.09.2012
Subjects
Animals
Cardiovascular
Disease Models, Animal
Heart Failure - physiopathology
Heart Ventricles - anatomy & histology
Heart Ventricles - embryology
Humans
Ventricular Dysfunction, Right - physiopathology
Ventricular Function, Left - physiology
Ventricular Function, Right - physiology
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Summary:Our ability to evaluate the right ventricle (RV) in pulmonary hypertension has traditionally been quite limited: the RV's complex anatomy is not adequately represented by 2-dimensional imaging, and our understanding of what is an adaptive and maladaptive RV response is incomplete. However, measures of RV function appear to be a strong predictor of survival in pulmonary hypertension. This is, therefore, a promising area for future study. To more fully understand the challenges and opportunities in this area, this article provides a review of RV embryology and anatomy, current assessment of the RV function, animal models of RV function, RV–pulmonary artery coupling, and how translating lessons from studies of the left ventricle may increase our knowledge of the RV.
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ISSN:0002-9149
1879-1913
1879-1913
DOI:10.1016/j.amjcard.2012.06.010