Changes in Antihypertensive Medication Following Bariatric Surgery

• Published in: Obesity surgery Vol. 32; no. 4; pp. 1312 - 1324
• Main Authors: Tajeu, Gabriel S., Johnson, Emily, Buccilla, Mason, Gadegbeku, Crystal A., Janick, Shane, Rubin, Daniel, Soans, Rohit, Eddy, Vikram J., Sarwer, David B.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2022; Springer Nature B.V
• Subjects: Adult; Antihypertensive Agents - therapeutic use; Antihypertensives; Bariatric Surgery; Gastrectomy; Gastric Bypass; Gastrointestinal surgery; Humans; Hypertension; Hypertension - drug therapy; Hypertension - surgery; Laparoscopy; Medicine; Medicine & Public Health; Obesity, Morbid - surgery; Review; Surgery; Treatment Outcome
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-022-05893-5

Obesity is a leading cause of hypertension (i.e., high blood pressure [BP]). While hypertension can be managed with antihypertensive medication, substantial weight loss can also lower BP, reducing the need for antihypertensive medication. Articles in this review ( n  = 60) presented data on antihypertensive medication use among adults pre- and postoperatively. Roux-en-Y gastric bypass was the most studied surgical approach followed by Laparoscopic Sleeve Gastrectomy. Antihypertensive medication was discontinued in a large proportion of patients after surgery, and the mean number of antihypertensive medications decreased by approximately one. In almost a third of the studies, over 75% of participants experienced hypertension remission. All articles aside from two reported a decrease in systolic BP, with about 40% reporting a decrease of ≥ 10 mm Hg.