Tumor-related prognostic factors for breast cancer

Interest in prognostic factors for breast cancer has been stimulated by the success of systemic adjuvant therapy for early-stage operable disease. Patients destined for recurrence can be selected for systemic adjuvant therapy, while patients not likely to recur can be spared the morbidity of unneces...

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Bibliographic Details
Published inCA: a cancer journal for clinicians Vol. 47; no. 1; pp. 28 - 51
Main Author Donegan, W. L
Format Journal Article
LanguageEnglish
Published Bristol Am Cancer Soc 01.01.1997
John Wiley & Sons, Ltd
Wiley Subscription Services, Inc
Subjects
Breast cancer
Breast Neoplasms - blood supply
Breast Neoplasms - diagnosis
Breast Neoplasms - genetics
Breast Neoplasms - pathology
Female
Humans
Lymphatic Metastasis
Mitosis
Neoplasm Staging
Neovascularization, Pathologic - pathology
Ploidies
Prognosis
Therapy
Tumors
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Summary:Interest in prognostic factors for breast cancer has been stimulated by the success of systemic adjuvant therapy for early-stage operable disease. Patients destined for recurrence can be selected for systemic adjuvant therapy, while patients not likely to recur can be spared the morbidity of unnecessary treatment. The number of tumor-related features available for prognosis has grown impressively in recent years. The purpose of this article is to review tumor-related biologic factors and relate them to prognosis and treatment objectives.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0007-9235
1542-4863
DOI:10.3322/canjclin.47.1.28