Genetic Variants of the IL‐23/IL‐17 Axis and Its Association With Periodontal Disease: A Systematic Review

• Published in: Immunity, Inflammation and Disease Vol. 13; no. 2; pp. e70147 - n/a
• Main Authors: Rodríguez‐Montaño, Ruth, Alarcón‐Sánchez, Mario Alberto, Lomelí‐Martínez, Sarah Monserrat, Martínez‐Bugarin, Cristina Hermila, Heboyan, Artak
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.02.2025; John Wiley and Sons Inc; Wiley
• Subjects: Adult; Coronaviruses; COVID-19; Cytokines; Fibroblasts; Genes; Genetic Predisposition to Disease; Genetic Variation; Gum disease; Humans; IL‐17; IL‐23; Interleukin-17 - genetics; Interleukin-23 - genetics; Kinases; Lymphocytes; Medical Subject Headings-MeSH; Microbiota; Periodontal Diseases - genetics; Periodontics; periodontitis; Periodontitis - genetics; peri‐implantitis; Polymorphism; Polymorphism, Single Nucleotide; Receptors, Interleukin - genetics; Receptors, Interleukin-17 - genetics; Review; Systematic review; Transplants & implants; Tumor necrosis factor-TNF; Vascular endothelial growth factor; IL‐23; peri‐implantitis; cytokines; IL‐17; genes; periodontitis

ABSTRACT Background The objective of this systematic review was to identify genetic variants of the IL‐23, IL‐17, IL‐23R and IL‐17R genes and isoforms and its possible association with increased development of periodontitis and peri‐implantitis. Methods A systematic review was prepared according to...