Role of the Melanocortin System in Inflammation

:  In recent years, scientific interest in melanocortins (MC) has progressively increased due to their wide range of effects and expression on various tissues.Primarily discovered as mediators of skin pigmentation, recent research has shown their important roles in various body functions, such as en...

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Published inAnnals of the New York Academy of Sciences Vol. 1072; no. 1; pp. 123 - 134
Main Authors MAASER, CHRISTIAN, KANNENGIESSER, KLAUS, KUCHARZIK, TORSTEN
Format Journal Article
LanguageEnglish
Published Malden, USA Blackwell Publishing Inc 01.08.2006
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Summary::  In recent years, scientific interest in melanocortins (MC) has progressively increased due to their wide range of effects and expression on various tissues.Primarily discovered as mediators of skin pigmentation, recent research has shown their important roles in various body functions, such as energy homeostasis, sexual function, and inflammation. The anti‐inflammatory and immunomodulatory properties discovered so far have led to the hypothesis that alpha‐melanocyte‐stimulating hormone (MSH) and its cognate receptors might present potential anti‐inflammatory treatment options.
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ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1326.016