Subclinical Thyroid Disease

Abstract Subclinical thyroid disease, a term applied to patients with no or minimal thyroid-related symptoms with abnormal laboratory values, is diagnosed more frequently with the use of thyroid-stimulating hormone (TSH) screening and newer high-sensitivity assays. These are laboratory diagnoses, wi...

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Bibliographic Details
Published inThe American journal of medicine Vol. 123; no. 6; pp. 502 - 504
Main Authors Jones, Dana D., MD, May, Katherine E., MD, Geraci, Stephen A., MD
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.06.2010
Elsevier
Elsevier Sequoia S.A
Subjects
Antithyroid Agents - administration & dosage
Antithyroid Agents - therapeutic use
Biological and medical sciences
Dose-Response Relationship, Drug
Endocrinopathies
General aspects
Hormones
Humans
Internal Medicine
Iodine Radioisotopes - administration & dosage
Management
Medical diagnosis
Medical sciences
Medical screening
Medical treatment
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Outpatient
Severity of Illness Index
Subclinical hyperthyroidism
Subclinical hypothyroidism
Thyroid diseases
Thyroid Diseases - blood
Thyroid Diseases - diagnosis
Thyroid Diseases - therapy
Thyroid. Thyroid axis (diseases)
Thyrotropin - blood
Thyroxine - administration & dosage
Thyroxine - blood
Treatment Outcome
Triiodothyronine - blood
Subclinical hyperthyroidism
Management
Outpatient
Subclinical hypothyroidism
Endocrinopathy
Medicine
Asymptomatic
Thyroid diseases
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Summary:Abstract Subclinical thyroid disease, a term applied to patients with no or minimal thyroid-related symptoms with abnormal laboratory values, is diagnosed more frequently with the use of thyroid-stimulating hormone (TSH) screening and newer high-sensitivity assays. These are laboratory diagnoses, with subclinical hypothyroidism defined as an elevated TSH with a normal free thyroxine and triiodothyronine concentration, and subclinical hyperthyroidism as a subnormal TSH with normal free thyroxine and triiodothyronine levels. Although studies defining which patients require treatment are few, decisions should be individualized based upon laboratory values and symptoms. This article reviews the etiologies, diagnoses, treatments and indications, and monitoring of patients with subclinical thyroid disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0002-9343
1555-7162
DOI:10.1016/j.amjmed.2009.12.023