Incorporating mechanical strain in organs-on-a-chip: Lung and skin

• Published in: Biomicrofluidics Vol. 12; no. 4; pp. 042207 - 42221
• Main Authors: Guenat, Olivier T., Berthiaume, François
• Format: Journal Article
• Language: English
• Published: United States American Institute of Physics 01.07.2018; AIP Publishing LLC
• Subjects: Actuation; Epithelium; Microfluidics; Organs; Platforms; Skin; SPECIAL TOPIC: BIO-TRANSPORT PROCESSES AND DRUG DELIVERY IN PHYSIOLOGICAL MICRO-DEVICES; Strain

In the last decade, the advent of microfabrication and microfluidics and an increased interest in cellular mechanobiology have triggered the development of novel microfluidic-based platforms. They aim to incorporate the mechanical strain environment that acts upon tissues and in-vivo barriers of the...