Consumption of tomato products is associated with lower blood mercury levels in Inuit preschool children

• Published in: Food and chemical toxicology Vol. 51; pp. 404 - 410
• Main Authors: Gagné, Doris, Lauzière, Julie, Blanchet, Rosanne, Vézina, Carole, Vaissière, Émilie, Ayotte, Pierre, Turgeon O’Brien, Huguette
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.01.2013; Elsevier
• Subjects: adverse effects; Animals; Antioxidants; atomic absorption spectrometry; Biological and medical sciences; Blood; breast feeding; Canada; Chemical and industrial products toxicology. Toxic occupational diseases; child care; child care centers; Child, Preschool; Consumption; Contaminants; Diet; Environmental Pollutants - blood; Female; Food Contamination; food frequency questionnaires; Foods; Humans; Infant; Inuit; Inuits; Lycopersicon esculentum; Male; Mathematical models; Meat; Medical sciences; Mercury; Mercury (metal); Mercury - blood; Metals and various inorganic compounds; nutrients; Odobenus rosmarus; Preschool children; Rangifer tarandus; Regression Analysis; Salvelinus alpinus; Seafood; seal meat; Seals, Earless; Tomato products; Toxicology; vegetables; Canada; Arctic region; Arctic Region; North America; America; Canada, Quebec; Canada, Quebec, Nunavik; PN, Arctic; Antioxidants; Canada; Inuit; Preschool children; Mercury; Tomato products; Preschool age; Consumption; Human; Biological fluid; Vegetables; Climacteric; Fruit vegetable; Antioxidant; Tomato; Blood; Heavy metal; Polar region; Child; Food
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2012.10.031

► 14% of participants had a blood mercury concentration above 40nmol/L. ► Regression analyses were performed after using multiple imputation. ► Consumption of tomato products, a proxy for lycopene intake, was negatively associated with mercury levels. ► Consumption of seal meat was positively associated with mercury levels. ► Age and breastfeeding duration were also positive predictors of mercury levels. Some evidence suggests that various diet components and nutrients, including vegetables, fruit and food-derived antioxidants, could mitigate contaminant exposure and/or adverse health effects of contaminants. To examine the effect of the consumption of tomato products on blood mercury levels in Inuit preschool children, 155 Inuit children (25.0±9.1months) were recruited from 2006–2008 in Nunavik childcare centers (northern Québec, Canada). Food frequency questionnaires were completed at home and at the childcare center, and total blood mercury concentration was measured by inductively coupled plasma-mass spectrometry. Multivariate regression analysis was performed after multiple imputation. The median blood concentration of mercury was 9.5nmol/L. Age, duration of breastfeeding, annual consumption frequency of seal meat, and monthly consumption frequency of tomato products were significant predictors of blood mercury levels, whereas annual consumption frequencies of beluga muktuk, walrus, Arctic char, and caribou meat were not. Each time a participant consumed tomato products during the month before the interview was associated with a 4.6% lower blood mercury level (p=0.0005). All other significant predictors in the model were positively associated with blood mercury levels. Further studies should explore interactions between consumption of healthy store-bought foods available in Arctic regions and contaminant exposure.