PCDD/PCDF, dl-PCB and PBDE serum levels of Slovak general population

• Published in: Chemosphere (Oxford) Vol. 88; no. 11; pp. 1383 - 1389
• Main Authors: CHOVANCOVA, Jana, CONKA, Kamil, FABISIKOVA, Anna, STACHOVA SEJAKOVA, Zuzana, DÖMÖTÖROVA, Milena, DROBNA, Beata, WIMMEROVA, Soňa
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.09.2012; Elsevier
• Subjects: Adult; adults; Aged; analogs & derivatives; Benzofurans; Benzofurans - blood; Biological and medical sciences; blood; Blood serum; Dibenzofurans, Polychlorinated; dl-PCBs; Environmental pollutants toxicology; Female; General aspects; Halogenated Diphenyl Ethers; Halogenated Diphenyl Ethers - blood; Humans; lipids; Male; Medical sciences; Middle Aged; PBDEs; PCDDs; PCDFs; plant industry; pollution; polychlorinated biphenyls; Polychlorinated Biphenyls - blood; polychlorinated dibenzodioxins; Polychlorinated Dibenzodioxins - analogs & derivatives; Polychlorinated Dibenzodioxins - blood; polychlorinated dibenzofurans; Slovakia; Toxicology; Young Adult; Europe; Slovakia; PCDFs; dl-PCBs; Slovakia; Blood serum; PCDDs; PBDEs; Human; Biological fluid; Dioxin derivatives; Polychlorobiphenyls; Flame retardant; Low volatile compound; Blood; Persistent organic pollutant; Concentration measurement; Polybrominated diphenyl ethers; Halogenated hydrocarbon; Chlorocarbon; Poison; Aromatic compound; Public health; Organic compounds
• ISSN: 0045-6535; 1879-1298; 1879-1298
• DOI: 10.1016/j.chemosphere.2012.05.060

► POP levels in serum of Slovak human population. ► Serum levels of TEQ PCDD/Fs and TEQ dl-PCBs higher in polluted areas than in the control area. ► Major PBDE congeners were BDE-47 and BDE-153. ► No correlation was found between donor age and PBDE content. ► Exposure of the Slovak population to PBDEs was significantly lower in comparison with other countries. Blood serum specimens from 81 non-occupationally exposed adults residing in four areas close to municipal and waste incinerators as well as metallurgical industry plant and 44 adult subjects coming from control area of Slovakia were analysed for polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), dioxin-like polychlorinated biphenyls (dl-PCBs) and polybrominated diphenylethers (PBDEs). The concentration of total WHO98TEQ PCDD/F/dl-PCBs in whole group of donors from areas where known sources causing dioxin contamination are present was significantly higher than in control group of donors (p<0.001). Correlation between the age of donors and PCDD/F and dl-PCB levels was confirmed (Spearman’s rPCDD/Fs=0.543, rdl-PCBs=0.521, p<0.001). Furthermore, this study presents first results concerning the PBDE congeners in human serum of Slovak general population. The total concentration (congeners 28, 47, 99, 100, 153, 154, 183) in control group was approximately 1.5-times higher in comparison to that of residents coming from areas with supposed environmental pollution. The most abundant congeners in all samples were BDE-47 and BDE-153 with median values of 0.24ngg−1 lipid and 0.23ngg−1 lipid, respectively. The positive association between PBDE values and age of donors was not found.