Replicase Complex Genes of Semliki Forest Virus Confer Lethal Neurovirulence

• Published in: Journal of Virology Vol. 74; no. 10; pp. 4579 - 4589
• Main Authors: Tuittila, M T, Santagati, M G, Röyttä, M, Määttä, J A, Hinkkanen, A E
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.05.2000
• Subjects: Alphavirus Infections - mortality; Alphavirus Infections - pathology; Alphavirus Infections - virology; Animals; Base Sequence; Brain - pathology; Brain - virology; Codon; Female; Gene Deletion; Genes, Viral; Genome, Viral; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutagenesis; Neurons - virology; neurovirology; NS3 gene; nsp3 gene; Rats; replicase; RNA Replicase - genetics; RNA, Viral - biosynthesis; Semliki Forest virus; Semliki forest virus - genetics; Semliki forest virus - pathogenicity; Viral Nonstructural Proteins - genetics; Viral Proteins - biosynthesis; Viral Structural Proteins - genetics; Viremia; Virulence - genetics; Virus Replication
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.74.10.4579-4589.2000

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