Current histological diagnosis of lymphomatoid granulomatosis

The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate t...

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Published inModern pathology Vol. 25; no. Suppl 1; pp. S39 - S42
Main Author Colby, Thomas V
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.01.2012
Elsevier Limited
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Online AccessGet full text
ISSN0893-3952
1530-0285
1530-0285
DOI10.1038/modpathol.2011.149

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Abstract The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.
AbstractList The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.
The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.
The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.
Author Colby, Thomas V
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Keywords lung
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LYG
lymphomatoid granulomatosis
lymphoma
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Snippet The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with...
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SubjectTerms 692/699/67/1990/291/1621/1915
692/700/139/422
B-Lymphocytes - immunology
B-Lymphocytes - pathology
Cells
Epstein-Barr virus
Herpesvirus 4, Human - immunology
Humans
Hybridization
Laboratory Medicine
long-course-article
Lung Neoplasms - diagnosis
Lung Neoplasms - immunology
Lung Neoplasms - pathology
Lymphoma
Lymphomatoid Granulomatosis - diagnosis
Lymphomatoid Granulomatosis - immunology
Lymphomatoid Granulomatosis - pathology
Medicine
Medicine & Public Health
Nervous system
Pathology
T-Lymphocytes - immunology
T-Lymphocytes - pathology
Title Current histological diagnosis of lymphomatoid granulomatosis
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https://www.ncbi.nlm.nih.gov/pubmed/22214969
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