The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species

We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob) to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensivel...

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Bibliographic Details
Published inGenome research Vol. 15; no. 10; pp. 1456 - 1461
Main Authors Byrne, Kevin P, Wolfe, Kenneth H
Format Journal Article
LanguageEnglish
Published United States Cold Spring Harbor Laboratory Press 01.10.2005
Subjects
Candida glabrata
Databases, Genetic
Genome, Fungal
Internet
Polyploidy
Resources
Saccharomyces castellii
Saccharomyces cerevisiae
Yeasts - genetics
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Summary:We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob) to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensively manually curated based on both sequence similarity and genomic context (synteny). We reconciled different laboratories' lists of paralogous Saccharomyces cerevisiae gene pairs formed by genome duplication (ohnologs), and present near-exhaustive lists of the ohnolog pairs retained in S. cerevisiae (551, including 22 previously unidentified), Saccharomyces castellii (599), and Candida glabrata (404).
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Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.3672305. Article published online before print in September 2005.
Corresponding author. E-mail khwolfe@tcd.ie ; fax 353-1-679-8558.
ISSN:1088-9051
1549-5469
DOI:10.1101/gr.3672305