Antimicrobial effect of oxidized cellulose salts

• Published in: Journal of industrial microbiology & biotechnology Vol. 35; no. 11; pp. 1247 - 1252
• Main Authors: Vytrasova, Jarmila, Tylsova, Andrea, Brozkova, Iveta, Cervenka, Libor, Pejchalova, Marcela, Havelka, Pavel
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.11.2008; Springer; Oxford University Press
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antifungal Agents - chemistry; Antifungal Agents - pharmacology; Antimicrobial agents; Aspergillus niger; Bacillus licheniformis; Bacteria; Bacteria - drug effects; Biochemistry; Bioinformatics; Biological and medical sciences; Biomedical and Life Sciences; Biotechnology; Candida albicans; Candida tropicalis; Cellulose; Cellulose, Oxidized - chemistry; Cellulose, Oxidized - pharmacology; Chemistry, Pharmaceutical; Clostridium perfringens; E coli; Escherichia coli; Fundamental and applied biological sciences. Psychology; Fungi; Fungi - drug effects; Genetic Engineering; Inorganic Chemistry; Life Sciences; Microbiology; Microorganisms; Original Paper; Oxidation; Penicillium chrysogenum; Pseudomonas aeruginosa; Rhizopus oryzae; Salts; Salts - chemistry; Salts - pharmacology; Scopulariopsis brevicaulis; Staphylococcus epidermidis; Studies; Yeast; Zinc; Minimal inhibition concentration; Oxidized cellulose; Antimicrobial properties; Zinc salts; Silver salts; Silver; Cellulose; Concentration; Inhibition; Antimicrobial agent; Zinc
• ISSN: 1367-5435; 1476-5535
• DOI: 10.1007/s10295-008-0421-y

Antimicrobial properties of oxidized cellulose and its salts in linters (-L) and microsphere (-M) form (OKCEL ® H-L, OKCEL ® Zn-M, OKCEL ® ZnNa-L, OKCEL ® ZnNa-M and OKCEL ® Ag-L) were tested by a dilution method against a spectrum of microbial strains: Escherichia coli , Pseudomonas aeruginosa , Staphylococcus epidermidis , Bacillus licheniformis , Aspergillus niger , Penicillium chrysogenum , Rhizopus oryzae , Scopulariopsis brevicaulis , Candida albicans and Candida tropicalis . OKCEL ® Ag-L exhibited antimicrobial activity in the range 0.1–3.5% w/v against all the bacteria and fungi involved in this study. Strong inhibition by OKCEL ® ZnNa-M was observed for Staphylococcus epidermidis , Bacillus licheniformis , Rhizopus oryzae , Candida albicans and Candida tropicalis in the range 0.5–2.0% w/v. Antimicrobial effects of oxidized cellulose and its salts in textile form were investigated by a diffusion and dilution method against the spectrum of above-cited microbial strains extended by Clostridium perfringens . Generally, OKCEL ® Ag-T, OKCEL ® Zn-T and OKCEL ® H-T showed high antimicrobial activity against populations of Pseudomonas aeruginosa , Bacillus licheniformis and Staphylococcus epidermidis. OKCEL ® Zn-T was the only sample suppressing the growth of species.