Control of the hematopoietic stem cell state

• Published in: Cell research Vol. 24; no. 1; pp. 3 - 4
• Main Authors: Knapp, David JHF, Eaves, Connie J
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2014; Nature Publishing Group
• Subjects: 631/136/232/1473/1542; 631/136/232/2051/1339; Animals; Biomedical and Life Sciences; Blood; Blood Platelets - cytology; Cell Biology; Cell Differentiation; Female; Hematopoietic Stem Cells - cytology; Life Sciences; Male; Research Highlight; Stem cells; 再生过程; 出版物; 控制; 细胞状态; 自我更新; 血小板; 识别标志; 造血干细胞
• ISSN: 1001-0602; 1748-7838; 1748-7838
• DOI: 10.1038/cr.2013.139

Several studies have demonstrated the clonal transmission of distinct differentiation and self-renewal properties in hematopoietic stem cells during the regeneration of blood production in transplanted recipients. A recent publication now identifies Vwf expression as a discriminating marker of a hem...