Copper-catalyzed N -arylation of amines with aryliodonium ylides in water
Copper sulfate catalyzed an efficient, inexpensive, and environment-friendly protocol that has been developed for -arylation of amines with 1,3-cyclohexadione-derived aryliodonium ylides in water as a green solvent. Aromatic primary amines substituted with electron-donating as well as electron-withd...
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Published in | Beilstein journal of organic chemistry Vol. 19; no. 1; pp. 1008 - 1014 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Germany
Beilstein-Institut zur Föerderung der Chemischen Wissenschaften
2023
Beilstein-Institut |
Subjects | |
Online Access | Get full text |
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Summary: | Copper sulfate catalyzed an efficient, inexpensive, and environment-friendly protocol that has been developed for
-arylation of amines with 1,3-cyclohexadione-derived aryliodonium ylides in water as a green solvent. Aromatic primary amines substituted with electron-donating as well as electron-withdrawing groups on the aryl ring reacted smoothly with iodonium ylides to give the corresponding diarylamines with good to excellent yields. Also, secondary amines underwent
-arylation to deliver tertiary amines with moderate yields. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1860-5397 2195-951X 1860-5397 |
DOI: | 10.3762/bjoc.19.76 |