Coexpression of intermediate-sized filaments in sialadenoma papilliferum and other salivary gland neoplasms

• Published in: Journal of oral pathology & medicine Vol. 19; no. 7; p. 313
• Main Authors: Nakahata, A, Deguchi, H, Yanagawa, T, Yoshida, H, Sato, M, Hayashi, Y
• Format: Journal Article
• Language: English
• Published: Denmark 01.08.1990
• Subjects: Adenocarcinoma - chemistry; Adenocarcinoma - ultrastructure; Adenolymphoma - chemistry; Adenolymphoma - ultrastructure; Adenoma, Pleomorphic - chemistry; Adenoma, Pleomorphic - ultrastructure; Carcinoma - chemistry; Carcinoma - ultrastructure; Carcinoma, Adenoid Cystic - chemistry; Carcinoma, Adenoid Cystic - ultrastructure; Desmin - analysis; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Intermediate Filaments - chemistry; Intermediate Filaments - ultrastructure; Keratins - analysis; Papilloma - chemistry; Papilloma - ultrastructure; Salivary Gland Neoplasms - chemistry; Salivary Gland Neoplasms - ultrastructure; Vimentin - analysis
• ISSN: 0904-2512
• DOI: 10.1111/j.1600-0714.1990.tb00851.x

The neoplastic cells present in a sialadenoma pappiliferum were found by immunoperoxidase method and immunofluorescent staining technique to co-express 3 different types of intermediate-sized filaments (IFs) defined by monoclonal antibodies to cytokeratin, vimentin and desmin. When other salivary gland tumors such as 18 pleomorphic adenomas, 15 adenolymphomas, 2 oxyphilic adenomas, 7 mucoepidermoid tumors, 5 acinic cell tumors, 8 adenoid cystic carcinomas and 6 adenocarcinomas were examined immunohistochemically for the expression of IFs, no tumors with all 3 types of IFs observed in sialadenoma papilliferum were found.