Distinct Role of Lycium barbarum L. Polysaccharides in Oxidative Stress-Related Ocular Diseases

Oxidative stress is an imbalance between the increased production of reactive species and reduced antioxidant activity, which can cause a variety of disturbances including ocular diseases. polysaccharides (LBPs) are complex polysaccharides isolated from the fruit of , showing distinct roles in antio...

Full description

Saved in:
Bibliographic Details
Published inPharmaceuticals (Basel, Switzerland) Vol. 16; no. 2; p. 215
Main Authors Niu, Yali, Zhang, Guoheng, Sun, Xiaojia, He, Shikun, Dou, Guorui
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 31.01.2023
MDPI
Subjects
age-related macular degeneration
Aging
Amino acids
antioxidant
Antioxidants
Biological activity
Carotenoids
Cataracts
Chinese medicine
Dendritic cells
Diabetes
Diabetic retinopathy
Enzymes
Flavonoids
Free radicals
Gene expression
hypertensive neuroretinopathy
Lycium barbarum polysaccharides
Macular degeneration
Methods
Oxidative stress
Polyphenols
Review
China
antioxidant
hypertensive neuroretinopathy
retinitis pigmentosa
Lycium barbarum polysaccharides
diabetic retinopathy
age-related macular degeneration
oxidative stress
Online AccessGet full text

Cover

More Information
Summary:Oxidative stress is an imbalance between the increased production of reactive species and reduced antioxidant activity, which can cause a variety of disturbances including ocular diseases. polysaccharides (LBPs) are complex polysaccharides isolated from the fruit of , showing distinct roles in antioxidants. Moreover, it is relatively safe and non-toxic. In recent years, the antioxidant activities of LBPs have attracted remarkable attention. In order to illustrate its significance and underlying therapeutic value for vision, we comprehensively review the recent progress on the antioxidant mechanisms of LBP and its potential applications in ocular diseases, including diabetic retinopathy, hypertensive neuroretinopathy, age-related macular degeneration, retinitis pigmentosa, retinal ischemia/reperfusion injury, glaucoma, dry eye syndrome, and diabetic cataract.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
These authors contributed equally to this work.
ISSN:1424-8247
1424-8247
DOI:10.3390/ph16020215