Surface Modification of Biodegradable Mg-Based Scaffolds for Human Mesenchymal Stem Cell Proliferation and Osteogenic Differentiation

• Published in: Materials Vol. 14; no. 2; p. 441
• Main Authors: Wang, Si-Han, Lee, Shiao-Pieng, Yang, Chung-Wei, Lo, Chun-Min
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 18.01.2021; MDPI
• Subjects: Alloys; Aqueous solutions; Biocompatibility; Biodegradability; biodegradation; Biomedical materials; bone tissue engineering; Bones; Cell adhesion & migration; Corrosion resistance; Crystal structure; Crystallites; Culture; Differentiation (biology); Fluorine; fluorohydroxyapatite; human mesenchymal stem cell; Hydroxyapatite; Magnesium; Magnesium base alloys; Mechanical properties; Metabolism; Physiology; Protective coatings; Regeneration (physiology); Scaffolds; Skin & tissue grafts; Stem cells; Substitute bone; Surgical implants; Tissue engineering; biodegradation; magnesium; fluorohydroxyapatite; bone tissue engineering; human mesenchymal stem cell

Magnesium alloys with coatings have the potential to be used for bone substitute alternatives since their mechanical properties are close to those of human bone. However, the surface modification of magnesium alloys to increase the surface biocompatibility and reduce the degradation rate remains a c...