Bariatric Surgery as Treatment Strategy of Obesity in Saudi People: Effects of Gut Microbiota

• Published in: Nutrients Vol. 15; no. 2; p. 361
• Main Authors: Alqahtani, Seham J, Alfawaz, Hanan A, Moubayed, Nadine M S, Hassan, Wail M, Almnaizel, Ahmad T, Alshiban, Noura M S, Abuhaimed, Jawahir M, Alahmed, Mohammed F, Al-Dagal, Mosffer M, El-Ansary, Afaf
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.01.2023; MDPI
• Subjects: Bacteria; bariatric surgery; Body composition; Body fat; Body mass index; Clinical medicine; Diabetes mellitus; Dietary restrictions; Digestive system; Dyslipidemia; Fatty liver; Feces; Gastrectomy; Gastrointestinal surgery; Gastrointestinal system; Gastrointestinal tract; gut microbiota; Health care; Health services; Hypertension; Intestinal microflora; Laparoscopic Sleeve Gastrectomy (LSG); Laparoscopy; Liver diseases; Metabolism; Microbiology; Microbiota; Microorganisms; Obesity; Overweight; Questionnaires; Surgery; Weight control; Saudi Arabia; United States > US; Laparoscopic Sleeve Gastrectomy (LSG); bariatric surgery; gut microbiota; obesity
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu15020361

Obesity prevalence is rising globally, as are the number of chronic disorders connected with obesity, such as diabetes, non-alcoholic fatty liver disease, dyslipidemia, and hypertension. Bariatric surgery is also becoming more common, and it remains the most effective and long-term treatment for obesity. This study will assess the influence of Laparoscopic Sleeve Gastrectomy (LSG) on gut microbiota in people with obesity before and after surgery. The findings shed new light on the changes in gut microbiota in Saudi people with obesity following LSG. In conclusion, LSG may improve the metabolic profile, resulting in decreased fat mass and increased lean mass, as well as improving the microbial composition balance in the gastrointestinal tract, but this is still not equivalent to normal weight microbiology. A range of factors, including patient characteristics, geographic dispersion, type of operation, technique, and nutritional and caloric restriction, could explain differences in abundance between studies. This information could point to a novel and, most likely, tailored strategy in obesity therapy, which could eventually be incorporated into health evaluations and monitoring in preventive health care or clinical medicine.