Association between Delayed Lactogenesis Ⅱ and Early Milk Volume among Mothers of Preterm Infants

• Published in: Asian nursing research Vol. 13; no. 2; pp. 93 - 98
• Main Authors: Yu, Xiurong, Li, Jianhua, Lin, Xiangyun, Luan, Dandan
• Format: Journal Article
• Language: English
• Published: Korea (South) Elsevier Limited 01.05.2019; Elsevier; 한국간호과학회
• Subjects: Adult; Babies; Breastfeeding & lactation; Cesarean section; Endocrine system; Female; Gestational Age; Gynecology; Humans; Infant, Newborn; Infant, Premature; Lactation; Lactation Disorders - epidemiology; Lactation Disorders - etiology; Lactation Disorders - physiopathology; Longitudinal Studies; Mothers; Newborn babies; Obstetrics; Postpartum period; Postpartum Period - physiology; Premature babies; Prevalence; Risk factors; 간호학; China; lactation; premature birth; milk, human
• ISSN: 1976-1317; 2093-7482
• DOI: 10.1016/j.anr.2019.02.001

This study aimed to evaluate the effect of delayed lactogenesis Ⅱ on early milk volume in mothers expressing milk for their preterm infants. 142 mothers with preterm infants participated in a longitudinal cohort study, the milk volumes over 14 days postpartum between mothers with delayed lactogenesis Ⅱ (≥ 72 hours) and mothers with non-delayed lactogenesis Ⅱ(< 72 hours) were compared using Wilcoxon's rank sum tests. The prevalence of delayed lactogenesisⅡ among mothers of preterm infants was 36.0% (36/100). There existed negative correlations between the onset of lactogenesis Ⅱ and the daily milk volumes( r = -0.525∼-0.354, p = .002 ∼ p < .001). The milk volumes in every 24-hour of the 14 days postpartum in delayed group were significantly less than that in non-delayed group (p = .002 ∼ p < .001). After controlling for the covariates, pregnancy-induced hypertension syndrome, delayed expression initiation, shorter daily sleeping time were found to be the risk factors for delayed lactogenesis Ⅱ. Delayed lactogenesis Ⅱ was associated with lower milk volume in early postpartum period. Women who were at risk for delayed lactogenesis Ⅱ need targeted interventions and additional support during pregnancy and postpartum.