Chemical Composition and In Vitro Antioxidant and Antimicrobial Activities of the Marine Cyanolichen Lichina pygmaea Volatile Compounds

• Published in: Marine drugs Vol. 20; no. 3; p. 169
• Main Authors: Sanad, Hiba, Belattmania, Zahira, Nafis, Ahmed, Hassouani, Meryem, Mazoir, Noureddine, Reani, Abdeltif, Hassani, Lahcen, Vasconcelos, Vitor, Sabour, Brahim
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25.02.2022; MDPI
• Subjects: Algae; Anti-Infective Agents - chemistry; Anti-Infective Agents - isolation & purification; Anti-Infective Agents - pharmacology; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; antioxidant and antimicrobial activities; Antioxidants; Antioxidants - chemistry; Antioxidants - isolation & purification; Antioxidants - pharmacology; Aquatic plants; Ascomycota - chemistry; Biofilms; Biphenyl Compounds - chemistry; Candida albicans - drug effects; Candida albicans - growth & development; Chemical composition; Cosmetics; Cyanobacteria; Disease resistance; E coli; Escherichia coli - drug effects; Escherichia coli - growth & development; Gas chromatography; Gram-negative bacteria; Lichens; Lichina pygmaea; Mass spectrometry; Mass spectroscopy; Metabolites; Minimum inhibitory concentration; Phenols; Picrates - chemistry; Pseudomonas aeruginosa; Pseudomonas aeruginosa - drug effects; Pseudomonas aeruginosa - growth & development; Scavenging; Sesquiterpenes; Sesquiterpenes - analysis; Sesquiterpenes - isolation & purification; Sesquiterpenes - pharmacology; Staphylococcus aureus - drug effects; Staphylococcus aureus - growth & development; VOCs; Volatile compounds; Volatile organic compounds; Volatile Organic Compounds - chemistry; Volatile Organic Compounds - isolation & purification; Volatile Organic Compounds - pharmacology; Morocco; volatile compounds; antioxidant and antimicrobial activities; Lichina pygmaea; chemical composition
• ISSN: 1660-3397; 1660-3397
• DOI: 10.3390/md20030169

Volatile compounds from the marine cyanolichen , collected from the Moroccan Atlantic coast, were extracted by hydrodistillation and their putative chemical composition was investigated by gas chromatography coupled to mass spectrometry (GC/MS). Based on the obtained results, volatile compounds (LPVCs) were mainly dominated by sesquiterpenes compounds, where -himachalene, -himachalene, ( )-2,4 decadienal and -himachalene were assumed to be the most abundant constituents, with percentage of 37.51%, 11.71%, 8.59% and 7.62%, respectively. LPVCs depicted significant antimicrobial activity against all tested strains ( CCMM B3, DSM 50090, ATCC 8739 and CCMM-L4) with minimum inhibitory concentration (MIC) values within the range of 1.69-13.5 mg/mL. Moreover, this LPVC showed interesting scavenging effects on the 2,2-diphenyl-1-picrylhydrazyl radical with an IC of 0.21 mg/mL. LPVCs could be an approving resource with moderate antimicrobial potential and interesting antioxidant activity for cosmetics and pharmaceutical applications.