Measurement of Intrahepatic Pressure during Microwave Ablation in an Ex Vivo Bovine Liver Model

• Published in: Gut and liver Vol. 9; no. 6; pp. 784 - 790
• Main Authors: Kim, Hae Jin, Rhim, Hyunchul, Lee, Min Woo, Jeong, Woo Kyoung
• Format: Journal Article
• Language: English
• Published: Korea (South) Editorial Office of Gut and Liver 01.11.2015; Gastroenterology Council for Gut and Liver; 거트앤리버 소화기연관학회협의회
• Subjects: Ablation Techniques - instrumentation; Ablation Techniques - methods; Animals; Cattle; ex vivo; intrahepatic pressure; liver; Liver - physiology; Liver - surgery; Medical Illustration; microwave ablation; Microwaves; Models, Animal; Original; Pressure; 내과학; Microwave ablation; Ex vivo; Intrahepatic pressure; Liver
• ISSN: 1976-2283; 2005-1212; 2005-1212
• DOI: 10.5009/gnl14272

We experimented with different ablation methods and two types of microwave antennas to determine whether microwave ablation (MWA) increases intrahepatic pressure and to identify an MWA protocol that avoids increasing intrahepatic pressure. MWA was performed using either a single-step standard ablation or a stepwise increment ablation paired with either a 16-gauge (G) 2-cm antenna or a 14G 4-cm antenna. We compared the maximum pressures and total ablation volumes. The mean maximum intrahepatic pressures and ablation volumes were as follows 16G single-step 37±33.4 mm Hg and 4.63 cm(3); 16G multistep 31±18.7 mm Hg and 3.75 cm(3); 14G single-step 114±45.4 mm Hg and 15.33 cm(3); and 14G multistep 106±43.8 mm Hg and 10.98 cm(3). The intrahepatic pressure rose during MWA, but there were no statistically significant differences between the single and multistep methods when the same gauge antennae were used. The total ablation volume was different only in the 14G groups (p<0.05). We demonstrated an increase in intrahepatic pressure during MWA. The multistep method may be used to prevent increased intrahepatic pressure after applying the proper power.