Metallic Biomaterials: Current Challenges and Opportunities

• Published in: Materials Vol. 10; no. 8; p. 884
• Main Authors: Prasad, Karthika, Bazaka, Olha, Chua, Ming, Rochford, Madison, Fedrick, Liam, Spoor, Jordan, Symes, Richard, Tieppo, Marcus, Collins, Cameron, Cao, Alex, Markwell, David, Ostrikov, Kostya (Ken), Bazaka, Kateryna
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 31.07.2017; MDPI
• Subjects: Biocompatibility; Biomedical materials; Dental implants; Pain; Review; Stability; Stents; Surgical implants; Three dimensional printing; Tissues; Transplants & implants; advanced materials; biomaterial; implant; inflammation; surface modification
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma10080884

Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.