Fabrication of Scaffolds for Bone-Tissue Regeneration

• Published in: Materials Vol. 12; no. 4; p. 568
• Main Authors: Chocholata, Petra, Kulda, Vlastimil, Babuska, Vaclav
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 14.02.2019; MDPI
• Subjects: Biological properties; Biomedical materials; Bones; Cell adhesion & migration; Chemical properties; Collagen; Defects; Dental implants; Dental materials; Dentin; Fractures; Growth factors; Immunology; Life sciences; Mammals; Membranes; Mineralization; Organic chemistry; Osteoblasts; Regeneration (physiology); Review; Stem cells; Surgical implants; Tissue engineering; Transplants & implants; stem cells; hydrogels; scaffolds; bone tissue engineering; regenerative medicine
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma12040568

The present article describes the state of the art in the rapidly developing field of bone tissue engineering, where many disciplines, such as material science, mechanical engineering, clinical medicine and genetics, are interconnected. The main objective is to restore and improve the function of bone tissue by scaffolds, providing a suitable environment for tissue regeneration and repair. Strategies and materials used in oral regenerative therapies correspond to techniques generally used in bone tissue engineering. Researchers are focusing on developing and improving new materials to imitate the native biological neighborhood as authentically as possible. The most promising is a combination of cells and matrices (scaffolds) that can be fabricated from different kinds of materials. This review summarizes currently available materials and manufacturing technologies of scaffolds for bone-tissue regeneration.