Use of antenatal corticosteroids in Brazil: data analysis from the National Survey Nascer no Brasil

• Published in: Revista Paulista de Pediatria Vol. 40; p. e2020126
• Main Authors: Cunha, Antônio José Ledo Alves da, Rezende, Karina Bilda de Castro, Moreira, Maria Elisabeth Lopes, Gama, Silvana Granado Nogueira da, Leal, Maria do Carmo
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade de Pediatria de São Paulo 01.01.2022
• Subjects: Adrenal Cortex Hormones; Brazil - epidemiology; Data Analysis; Female; Humans; Infant; Infant, Newborn; Obstetric labor, premature; Original; Parity; Pregnancy; Prenatal Care; Primary prevention; Risk factors; Brazil
• ISSN: 0103-0582; 1984-0462
• DOI: 10.1590/1984-0462/2022/40/2020126

To estimate the rate of the use of antenatal corticosteroids (ANC) among pregnant women and to identify the conditions associated with their non-use in Brazil. Secondary data analysis from "Birth in Brazil", a national hospital-based survey carried out in 2011-2012 on childbirth and birth. The sample was characterized regarding maternal age, marital status and maternal education, parity, mode of delivery and place of residence. The association of ANC use with gestational age and type of delivery was analyzed. The studied maternal complications were the presence of hypertension, pre-eclampsia/eclampsia, and pyelonephritis, infection by the HIV virus or acquired immune deficiency syndrome. 2,623 pregnant women with less than 37 weeks of gestational age were identified, and, of these, 835 (31.8%) received ANC. The frequency of ANC use was higher among women with gestational ages between 26-34 weeks (481 cases; 48.73%). In pregnancies with less than 37 weeks, the use of ANC was 23.9% in spontaneous deliveries, 20.6% in induced deliveries and 43.8% among those who did not go into labor. The variables vaginal delivery (OR 2.5; 95%CI 1.8-3.4) and living in the countryside were associated with not using ANC, and the occurrence of pre-eclampsia/eclampsia (OR 1.8; 95%CI 1.2-2.9) was associated with the use of ANC. The use of ANC among Brazilian pregnant women was low. Interventions to increase its use are necessary and can contribute to reduce neonatal mortality and morbidity. ANC should be promoted in pregnancies of less than 37 weeks, especially in cases of vaginal delivery and for those living in the countryside.