Strontium ions substitution in brushite crystals: the role of strontium chloride

The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly incre...

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Published inJournal of functional biomaterials Vol. 2; no. 2; pp. 31 - 38
Main Authors Alkhraisat, Mohammad H, Rueda, Carmen, López Cabarcos, Enrique
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 31.05.2011
MDPI
Subjects
Brushite
calcium phosphate cement
glycolic acid
strontium
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Summary:The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.
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ISSN:2079-4983
2079-4983
DOI:10.3390/jfb2020031