Association between Use of Nutrition Labels and Risk of Chronic Kidney Disease: The Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2019

• Published in: Nutrients Vol. 14; no. 9; p. 1731
• Main Authors: Kim, Jonghee, Dorgan, Joanne F, Kim, Hyesook, Kwon, Oran, Kim, Yangha, Kim, Yuri, Ko, Kwang Suk, Park, Yoon Jung, Park, Hyesook, Jung, Seungyoun
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.04.2022; MDPI
• Subjects: Adults; Aged; Chronic illnesses; chronic kidney disease (CKD); CKD prognostic risk; Creatinine; Cross-Sectional Studies; Descriptive labeling; Diet; Female; Food; Food Labeling; Glomerular Filtration Rate; Health care; Health risks; Humans; Kidney diseases; Kidneys; Korean National Health and Nutrition Examination Survey; Labels; Lifestyles; Male; Middle Aged; Nutrition; nutrition label awareness; nutrition label use; nutrition labels; Nutrition research; Nutrition Surveys; Older people; Population; Proteins; Proteinuria; Purchasing; Questionnaires; Regression analysis; Renal Insufficiency, Chronic - epidemiology; Renal Insufficiency, Chronic - etiology; Renal Insufficiency, Chronic - prevention & control; Republic of Korea - epidemiology; Risk management; Republic of Korea; nutrition labels; CKD prognostic risk; nutrition label awareness; chronic kidney disease (CKD); nutrition label use; Korean National Health and Nutrition Examination Survey
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu14091731

Nutrition labeling on food packages is increasingly found to promote healthier food choices associated with lower risk of chronic kidney disease (CKD). To examine associations between nutrition labels use and CKD risk, we conducted a nationally representative cross-sectional study of 32,080 adults from the 2008−2019 Korean National Health and Nutrition Examination Survey. Nutrition labels use was collected via self-reported questionnaires. Ascertainment and severity of CKD was determined by estimated glomerular filtration rate or proteinuria. In multivariable-adjusted (MV) logistic regression models, increasing awareness and use of nutrition labels was significantly associated with lower CKD risk (MV-adjusted OR “nutrition labels aware and use” group vs. “nutrition labels unaware” group [95% CIs]: 0.75 [0.59−0.95], Ptrend:0.03). This inverse association varied with CKD’s risk of progression, with 21% and 42% reduced risk observed for CKD subtypes with “moderate” and “high” risk of progression, respectively (all Ptrend ≤ 0.04). Furthermore, the nutrition labels use and CKD risk association significantly differed by age, with 35% reduced risk observed in the older group aged 49 years or older, but not in the younger group (Pinteraction < 0.001). Our results suggest increasing perception and use of nutrition labels may contribute to CKD prevention and its early asymptomatic progression, especially in older adults.